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2HD6

Crystal structure of the human carbonic anhydrase II in complex with a hypoxia-activatable sulfonamide.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ACarbonic anhydrase 2polymer25929157.91UniProt (P00918)
Pfam (PF00194)
In PDB
Homo sapiens (human)Carbonic anhydrase II, Carbonate dehydratase II, CA-II, Carbonic anhydrase C
2AZINC IONnon-polymer65.41Chemie (ZN)
3ACHLORIDE IONnon-polymer35.51Chemie (CL)
4AMERCURIBENZOIC ACIDnon-polymer321.71Chemie (MBO)
5AN-[4-(AMINOSULFONYL)PHENYL]-2-MERCAPTOBENZAMIDEnon-polymer308.41Chemie (BOS)
6AGLYCEROLnon-polymer92.11Chemie (GOL)
7waterwater18.0230Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight29157.9
Non-Polymers*Number of molecules5
Total formula weight823.0
All*Total formula weight29980.9
*Water molecules are not included.

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PDB entries from 2024-04-24

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