2HCH

N-Domain Of Grp94 In Complex With the Novel Ligand N-(2-amino)ethyl Carboxyamido Adenosine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Endoplasmin	polymer	236	26514.0	2	UniProt (P41148) Pfam (PF13589) In PDB	Canis lupus familiaris (dog)	Heat shock protein 90 kDa beta member 1, 94 kDa glucose-regulated protein, GRP94
2	A, B	5'-N-[(2-AMINO)ETHYL CARBOXAMIDO] ADENOSINE	non-polymer		323.3	2	Chemie (N5A)
3	A, B	TETRAETHYLENE GLYCOL	non-polymer		194.2	5	Chemie (PG4)
4	B	PENTAETHYLENE GLYCOL	non-polymer		238.3	1	Chemie (1PE)
5		water	water		18.0	193	Chemie (HOH)

Sequence modifications

A, B: 69 - 286 (UniProt: P41148)

PDB	External Database	Details
Gly 65	-	cloning artifact
Ser 66	-	cloning artifact
His 67	-	cloning artifact
Met 68	-	cloning artifact

A, B: 328 - 337 (UniProt: P41148)

PDB	External Database	Details
Gly 287	-	SEE REMARK 999
Gly 288	-	SEE REMARK 999
Gly 289	-	SEE REMARK 999
Gly 290	-	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	53028.0
Non-Polymers*	Number of molecules	8
	Total formula weight	1856.0
All*	Total formula weight	54884.0

*Water molecules are not included.