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2HC1

Engineered catalytic domain of protein tyrosine phosphatase HPTPbeta.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AReceptor-type tyrosine-protein phosphatase betapolymer29133780.31UniProt (P23467)
Pfam (PF00102)
In PDB
Homo sapiens (human)Protein-tyrosine phosphatase beta, R-PTP-beta
2AACETATE IONnon-polymer59.01Chemie (ACT)
3ACHLORIDE IONnon-polymer35.52Chemie (CL)
4waterwater18.0362Chemie (HOH)
Sequence modifications
A: 1676 - 1965 (UniProt: P23467)
PDBExternal DatabaseDetails
Ser 1675-cloning artifact
-Asn 1748deletion
-Val 1749deletion
-Asp 1750deletion
-Asp 1751deletion
-Asp 1752deletion
Gly 1748Pro 1753engineered mutation
Gly 1749Cys 1754engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight33780.3
Non-Polymers*Number of molecules3
Total formula weight129.9
All*Total formula weight33910.3
*Water molecules are not included.

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PDB entries from 2024-06-12

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