2HA4
Crystal structure of mutant S203A of mouse acetylcholinesterase complexed with acetylcholine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Acetylcholinesterase | polymer | 543 | 59748.5 | 2 | UniProt (P21836) Pfam (PF00135) | Mus musculus (house mouse) | AChE |
| 2 | C, G (A, B) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 3 | D, E, H, I (A, B) | ACETYLCHOLINE | non-polymer | 146.2 | 4 | Chemie (ACH) | |||
| 4 | F (A) | HEXAETHYLENE GLYCOL | non-polymer | 282.3 | 1 | Chemie (P6G) | |||
| 5 | J, K (A, B) | water | water | 18.0 | 421 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 543 (UniProt: P21836)
| PDB | External Database | Details |
|---|---|---|
| Ala 203 | Ser 234 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 119497.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 985.2 | |
| All* | Total formula weight | 120482.2 |
