2H7V
Co-crystal structure of YpkA-Rac1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Migration-inducing protein 5 | polymer | 188 | 20789.1 | 2 | UniProt (P63000) Pfam (PF00071) | Homo sapiens (human) | Ras-related C3 botulinum toxin substrate 1, isoform Rac1 |
| 2 | C, D (C, D) | Protein kinase ypkA | polymer | 303 | 34449.0 | 2 | UniProt (Q05608) Pfam (PF09632) | Yersinia pseudotuberculosis | Protein kinase A, Targeted effector protein kinase |
| 3 | E, G (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | F, H (A, B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
| 5 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 75 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 184 (UniProt: P63000)
C, D: 434 - 732 (UniProt: Q05608)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | cloning artifact |
| Ser 2 | - | cloning artifact |
| Lys 1 | - | cloning artifact |
| Leu 2 | - | cloning artifact |
| Ser 78 | Phe 78 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 430 | - | cloning artifact |
| Pro 431 | - | cloning artifact |
| Val 432 | - | cloning artifact |
| Asp 433 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 110476.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 935.0 | |
| All* | Total formula weight | 111411.3 |
