2H7V
Co-crystal structure of YpkA-Rac1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Migration-inducing protein 5 | polymer | 188 | 20789.1 | 2 | UniProt (P63000) Pfam (PF00071) | Homo sapiens (human) | Ras-related C3 botulinum toxin substrate 1, isoform Rac1 |
| 2 | C, D (C, D) | Protein kinase ypkA | polymer | 303 | 34449.0 | 2 | UniProt (Q05608) | Yersinia pseudotuberculosis | Protein kinase A, Targeted effector protein kinase |
| 3 | E, G (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 4 | F, H (A, B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 5 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 75 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 184 (UniProt: P63000)
C, D: 434 - 732 (UniProt: Q05608)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | cloning artifact |
| Ser 2 | - | cloning artifact |
| Lys 1 | - | cloning artifact |
| Leu 2 | - | cloning artifact |
| Ser 78 | Phe 78 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 430 | - | cloning artifact |
| Pro 431 | - | cloning artifact |
| Val 432 | - | cloning artifact |
| Asp 433 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 110476.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 935.0 | |
| All* | Total formula weight | 111411.3 |
