2H7C
Crystal structure of human carboxylesterase in complex with Coenzyme A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | Liver carboxylesterase 1 | polymer | 542 | 59787.5 | 6 | UniProt (P23141) Pfam (PF00135) In PDB | Homo sapiens (human) | Acyl coenzyme A:cholesterol acyltransferase, ACAT, Monocyte/macrophage serine esterase, HMSE, Serine esterase 1, Brain carboxylesterase hBr1, Triacylglycerol hydrolase, TGH, Egasyn |
| 2 | G, H | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 3 | E, F, A, B, C... | SULFATE ION | non-polymer | 96.1 | 12 | Chemie (SO4) | |||
| 4 | E, F, A, B, C... | COENZYME A | non-polymer | 767.5 | 6 | Chemie (COA) | |||
| 5 | B, C, D, E | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 6 | E, D | N-acetyl-alpha-neuraminic acid | non-polymer | 309.3 | 2 | Chemie (SIA) | |||
| 7 | water | water | 18.0 | 2715 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1019 - 1561 (UniProt: P23141)
| PDB | External Database | Details |
|---|---|---|
| - | Gln 362 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 358725.2 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 7261.3 | |
| All* | Total formula weight | 366835.3 |
