2H65
Crystal strusture of caspase-3 with inhibitor Ac-VDVAD-Cho
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | caspase-3, p17 subunit | polymer | 146 | 16524.8 | 2 | UniProt (P42574) Pfam (PF00656) | Homo sapiens (human) | CASP-3; Apopain; Cysteine protease CPP32; Yama protein; CPP-32; SREBP cleavage activity 1; SCA-1 |
| 2 | B, D (B, D) | caspase-3, p12 subunit | polymer | 95 | 11258.0 | 2 | UniProt (P42574) Pfam (PF00656) | Homo sapiens (human) | |
| 3 | E, F (E, F) | Ac-VDVAD-Cho | polymer | 6 | 529.6 | 2 | BIRD (PRD_000425) | ||
| 4 | G, H, I, J, K (A, B, C, D, F) | water | water | 18.0 | 86 | Chemie (HOH) |
Sequence modifications
B, D: 184 - 277 (UniProt: P42574)
| PDB | External Database | Details |
|---|---|---|
| His 278 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 56624.7 | |
| All* | Total formula weight | 56624.7 |
