2H62
Crystal structure of a ternary ligand-receptor complex of BMP-2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bone morphogenetic protein 2 | polymer | 114 | 12923.9 | 2 | UniProt (P12643) Pfam (PF00019) | Homo sapiens (human) | BMP-2, BMP-2A |
| 2 | C (C) | Bone morphogenetic protein receptor type IA | polymer | 129 | 14199.9 | 1 | UniProt (P36894) Pfam (PF01064) | Homo sapiens (human) | Serine/threonine-protein kinase receptor R5, SKR5, Activin receptor-like kinase 3, ALK-3, CD292 antigen |
| 3 | D (D) | Acvr2b protein | polymer | 98 | 11551.7 | 1 | UniProt (Q3KQI1) Pfam (PF01064) UniProt (by SIFTS) (Q13705) | Homo sapiens (human) | Activin receptor type IIB |
| 4 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 288 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 51599.3 | |
| All* | Total formula weight | 51599.3 |
