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2H4K

Crystal structure of PTP1B with a monocyclic thiophene inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Tyrosine-protein phosphatase non-receptor type 1polymer29934833.71UniProt (P18031)
Pfam (PF00102)
Homo sapiens (human)Protein-tyrosine phosphatase 1B, PTP-1B
2B
(A)
4-BROMO-3-(CARBOXYMETHOXY)-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACIDnon-polymer357.21Chemie (509)
3C
(A)
waterwater18.0112Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight34833.7
Non-Polymers*Number of molecules1
Total formula weight357.2
All*Total formula weight35190.9
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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