2H3N

Crystal structure of a surrogate light chain (LAMBDA5 and VpreB) homodimer

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	VpreB protein	polymer	100	11346.8	2	UniProt (P12018) Pfam (PF07686)	Homo sapiens (human)	Immunoglobulin iota chain; V(pre)B protein; CD179a antigen
2	B, D (B, D)	Ig lambda-5	polymer	117	12722.3	2	UniProt (P15814) Pfam (PF07654)	Homo sapiens (human)	Immunoglobulin lambda-like polypeptide 1; Immunoglobulin-related protein 14.1; Immunoglobulin omega polypeptide; CD179b antigen
3	E, F, G, H (A, B, C, D)	water	water		18.0	68	Chemie (HOH)

Sequence modifications

A, C: 2 - 100 (UniProt: P12018)

PDB	External Database	Details
Gln 1	-	cloning artifact

B, D: 57 - 172 (UniProt: P15814)

PDB	External Database	Details
Ala 173	-	cloning artifact

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	48138.1
All*	Total formula weight	48138.1

*Water molecules are not included.