2H34

Apoenzyme crystal structure of the tuberculosis serine/threonine kinase, PknE

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Serine/threonine-protein kinase pknE	polymer	309	34058.2	2	UniProt (P72001) Pfam (PF00069) UniProt (by SIFTS) (P9WI77) In PDB	Mycobacterium tuberculosis
2	A	BROMIDE ION	non-polymer		79.9	1	Chemie (BR)
3	A, B	SODIUM ION	non-polymer		23.0	2	Chemie (NA)

Sequence modifications

A, B: 1 - 289 (UniProt: P72001)

PDB	External Database	Details
Met 1	-	EXPRESSION TAG
Gly -18	-	EXPRESSION TAG
Ser -17	-	EXPRESSION TAG
Ser -16	-	EXPRESSION TAG
His -15	-	EXPRESSION TAG
His -14	-	EXPRESSION TAG
His -13	-	EXPRESSION TAG
His -12	-	EXPRESSION TAG
His -11	-	EXPRESSION TAG
His -10	-	EXPRESSION TAG
Ser -9	-	EXPRESSION TAG
Ser -8	-	EXPRESSION TAG
Gly -7	-	EXPRESSION TAG
Leu -6	-	EXPRESSION TAG
Val -5	-	EXPRESSION TAG
Pro -4	-	EXPRESSION TAG
Arg 17	-	EXPRESSION TAG
Gly -2	-	EXPRESSION TAG
Ser -1	-	EXPRESSION TAG
His 0	-	EXPRESSION TAG
Mse 27	Met 27	MODIFIED RESIDUE
Mse 47	Met 47	MODIFIED RESIDUE
Mse 61	Met 61	MODIFIED RESIDUE
Mse 93	Met 93	MODIFIED RESIDUE
Mse 104	Met 104	MODIFIED RESIDUE
Mse 182	Met 182	MODIFIED RESIDUE
Mse 223	Met 223	MODIFIED RESIDUE
Mse 253	Met 253	MODIFIED RESIDUE

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	68116.3
Non-Polymers*	Number of molecules	3
	Total formula weight	125.9
All*	Total formula weight	68242.2

*Water molecules are not included.