2H2U
Crystal structure of the E130Y mutant of human soluble calcium-activated nucleotidase (SCAN) with calcium ion
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Soluble calcium-activated nucleotidase 1 | polymer | 339 | 37842.1 | 2 | UniProt (Q8WVQ1) Pfam (PF06079) | Homo sapiens (human) | SCAN-1, Apyrase homolog, Putative NF-kappa-B-activating protein 107, Putative MAPK-activating protein PM09 |
| 2 | C, D (A, B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 29 | Chemie (HOH) |
Sequence modifications
A, B: -1 - 331 (UniProt: Q8WVQ1)
| PDB | External Database | Details |
|---|---|---|
| Gly -7 | - | cloning artifact |
| Ser -6 | - | cloning artifact |
| His -5 | - | cloning artifact |
| Met -4 | - | cloning artifact |
| Ala -3 | - | cloning artifact |
| Ser -2 | - | cloning artifact |
| Tyr 90 | Glu 160 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 75684.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 80.2 | |
| All* | Total formula weight | 75764.4 |
