2H15
Carbonic anhydrase inhibitors: Clashing with Ala65 as a means of designing isozyme-selective inhibitors that show low affinity for the ubiquitous isozyme II
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Carbonic anhydrase 2 | polymer | 260 | 29289.1 | 1 | UniProt (P00918) Pfam (PF00194) | Homo sapiens (human) | Carbonic anhydrase II, Carbonate dehydratase II, CA-II, Carbonic anhydrase C |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | MERCURY (II) ION | non-polymer | 200.6 | 1 | Chemie (HG) | |||
| 4 | D (A) | N-{[(3AS,5AR,8AR,8BS)-2,2,7,7-TETRAMETHYLTETRAHYDRO-3AH-BIS[1,3]DIOXOLO[4,5-B:4',5'-D]PYRAN-3A-YL]METHYL}SULFAMIDE | non-polymer | 338.4 | 1 | Chemie (B19) | |||
| 5 | E (A) | water | water | 18.0 | 182 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29289.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 604.4 | |
| All* | Total formula weight | 29893.4 |
