2GW2

Crystal structure of the peptidyl-prolyl isomerase domain of human cyclophilin G

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Peptidyl-prolyl cis-trans isomerase G	polymer	198	21842.7	1	UniProt (Q13427) Pfam (PF00160) In PDB	Homo sapiens (human)	Peptidyl-prolyl isomerase G, PPIase G, Rotamase G, Cyclophilin G, Clk-associating RS-cyclophilin, CARS-cyclophilin, CARS-Cyp, SR-cyclophilin, SRcyp, SR-cyp, CASP10
2	A	UNKNOWN ATOM OR ION	non-polymer			4	Chemie (UNX)
3		water	water		18.0	103	Chemie (HOH)

Sequence modifications

A: 1 - 179 (UniProt: Q13427)

PDB	External Database	Details
Met -18	-	cloning artifact
Gly -17	-	cloning artifact
Ser -16	-	cloning artifact
Ser -15	-	cloning artifact
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
Ser -8	-	cloning artifact
Ser -7	-	cloning artifact
Gly -6	-	cloning artifact
Leu -5	-	cloning artifact
Val -4	-	cloning artifact
Pro -3	-	cloning artifact
Arg -2	-	cloning artifact
Gly -1	-	cloning artifact
Ser 0	-	cloning artifact
Ala 106	Lys 106	engineered mutation
Ala 107	Glu 107	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	21842.7
Non-Polymers*	Number of molecules	4
	Total formula weight	0.0
All*	Total formula weight	21842.7

*Water molecules are not included.