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2GV6

Crystal Structure of Matriptase with Inhibitor CJ-730

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Suppressor of tumorigenicity 14polymer24126463.81UniProt (Q9Y5Y6)
Pfam (PF00089)
Homo sapiens (human)Serine protease 14, Matriptase, Membrane-type serine protease 1, MT-SP1, Prostamin, Serine protease TADG-15, Tumor-associated differentially-expressed gene 15 protein
2B
(A)
(S)-3-(3-(4-(2-GUANIDINOETHYL)PIPERIDIN-1-YL)-2-(NAPHTHALENE-2-SULFONAMIDO)-3-OXOPROPYL)BENZIMIDAMIDEnon-polymer549.71Chemie (730)
3C
(A)
waterwater18.0244Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight26463.8
Non-Polymers*Number of molecules1
Total formula weight549.7
All*Total formula weight27013.4
*Water molecules are not included.

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PDB entries from 2025-11-12

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