2GTK
Structure-based Design of Indole Propionic Acids as Novel PPARag CO-Agonists
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Peroxisome proliferator-activated receptor gamma | polymer | 271 | 30997.0 | 1 | UniProt (P37231) Pfam (PF00104) | Homo sapiens (human) | PPARg-LBD; PPAR-gamma |
| 2 | B (B) | Decamer from Nuclear receptor coactivator 1 | polymer | 10 | 1155.4 | 1 | UniProt (Q15788) | ||
| 3 | C (A) | (2S)-3-(1-{[2-(2-CHLOROPHENYL)-5-METHYL-1,3-OXAZOL-4-YL]METHYL}-1H-INDOL-5-YL)-2-ETHOXYPROPANOIC ACID | non-polymer | 438.9 | 1 | Chemie (208) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 254 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 32152.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 438.9 | |
| All* | Total formula weight | 32591.3 |
