2GTI
mutation of MHV coronavirus non-structural protein nsp15 (F307L)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Replicase polyprotein 1ab | polymer | 370 | 41897.7 | 1 | UniProt (P16342) Pfam (PF19219) Pfam (PF19216) Pfam (PF19215) UniProt (by SIFTS) (P0C6X9) | Murine hepatitis virus | pp1ab, ORF1ab polyprotein, non-structural protein nsp15 |
| 2 | B, C, D, E, F... (A) | SULFATE ION | non-polymer | 96.1 | 8 | Chemie (SO4) | |||
| 3 | J, K (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | L (A) | water | water | 18.0 | 264 | Chemie (HOH) |
Sequence modifications
A: 1 - 369 (UniProt: P16342)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | cloning artifact |
| Mse 147 | Met 6650 | modified residue |
| Mse 237 | Met 6740 | modified residue |
| Mse 242 | Met 6745 | modified residue |
| Leu 307 | Phe 6810 | engineered mutation |
| Mse 358 | Met 6861 | modified residue |
| Mse 367 | Met 6870 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41897.7 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 952.7 | |
| All* | Total formula weight | 42850.4 |
