2GRA
crystal structure of Human Pyrroline-5-carboxylate Reductase complexed with nadp
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | Pyrroline-5-carboxylate reductase 1 | polymer | 277 | 29147.6 | 5 | UniProt (P32322) Pfam (PF03807) Pfam (PF14748) | Homo sapiens (human) | P5CR 1, P5C reductase 1 |
| 2 | F, H, J, L, N (A, B, C, D, E) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 5 | Chemie (NAP) | |||
| 3 | G, I, K, M, O (A, B, C, D, E) | GLUTAMIC ACID | non-polymer | 147.1 | 5 | Chemie (GLU) | |||
| 4 | P, Q, R, S, T (A, B, C, D, E) | water | water | 18.0 | 620 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 1 - 275 (UniProt: P32322)
| PDB | External Database | Details |
|---|---|---|
| Arg -1 | - | cloning artifact |
| Gly 0 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 145738.2 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 4452.7 | |
| All* | Total formula weight | 150190.9 |
