2GP0
HePTP Catalytic Domain (residues 44-339), S225D mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tyrosine-protein phosphatase non-receptor type 7 | polymer | 309 | 35364.0 | 1 | UniProt (P35236) Pfam (PF00102) | Homo sapiens (human) | Protein-tyrosine phosphatase LC-PTP, Hematopoietic protein-tyrosine phosphatase, HEPTP |
| 2 | B (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 3 | C (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | D (A) | water | water | 18.0 | 297 | Chemie (HOH) |
Sequence modifications
A: 44 - 339 (UniProt: P35236)
| PDB | External Database | Details |
|---|---|---|
| Met 31 | - | expression tag |
| Gly 32 | - | expression tag |
| Ser 33 | - | expression tag |
| Asp 34 | - | expression tag |
| Lys 35 | - | expression tag |
| Ile 36 | - | expression tag |
| His 37 | - | expression tag |
| His 38 | - | expression tag |
| His 39 | - | expression tag |
| His 40 | - | expression tag |
| His 41 | - | expression tag |
| His 42 | - | expression tag |
| Met 43 | - | expression tag |
| Asp 225 | Ser 246 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35364.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 187.1 | |
| All* | Total formula weight | 35551.1 |
