2GN4
Crystal structure of UDP-GlcNAc inverting 4,6-dehydratase in complex with NADPH and UDP-GlcNAc
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | UDP-GlcNAc C6 dehydratase | polymer | 344 | 38724.7 | 2 | UniProt (O25511) Pfam (PF02719) | Helicobacter pylori | flaA1 protein |
| 2 | C, E (A, B) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) | |||
| 3 | D, F (A, B) | URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE | non-polymer | 607.4 | 2 | Chemie (UD1) | |||
| 4 | G, H (B) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 2 | Chemie (MES) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 308 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 333 (UniProt: O25511)
| PDB | External Database | Details |
|---|---|---|
| Met -10 | - | cloning artifact |
| His -9 | - | expression tag |
| His -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| Gly -3 | - | cloning artifact |
| Ser -2 | - | cloning artifact |
| Met -1 | - | cloning artifact |
| Ser 0 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 77449.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 3096.0 | |
| All* | Total formula weight | 80545.4 |
