2GN4

Crystal structure of UDP-GlcNAc inverting 4,6-dehydratase in complex with NADPH and UDP-GlcNAc

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	UDP-GlcNAc C6 dehydratase	polymer	344	38724.7	2	UniProt (O25511) Pfam (PF02719) In PDB	Helicobacter pylori	flaA1 protein
2	A, B	NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		745.4	2	Chemie (NDP)
3	A, B	URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE	non-polymer		607.4	2	Chemie (UD1)
4	B	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	2	Chemie (MES)
5		water	water		18.0	308	Chemie (HOH)

Sequence modifications

A, B: 1 - 333 (UniProt: O25511)

PDB	External Database	Details
Met -10	-	cloning artifact
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
Gly -3	-	cloning artifact
Ser -2	-	cloning artifact
Met -1	-	cloning artifact
Ser 0	-	cloning artifact

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	77449.4
Non-Polymers*	Number of molecules	6
	Total formula weight	3096.0
All*	Total formula weight	80545.4

*Water molecules are not included.