2GKI
Heavy and light chain variable single domains of an anti-DNA binding antibody hydrolyze both double- and single-stranded DNAs without sequence specificity
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | nuclease | polymer | 291 | 31504.3 | 2 | GenBank (8777863) GenBank (8777865) Pfam (PF07686) UniProt (by SIFTS) (A0N274) | Mus musculus (house mouse) | |
| 2 | C, D (A, B) | water | water | 18.0 | 70 | Chemie (HOH) |
Sequence modifications
A, B: 23 - 142 (GenBank: 8777863)
A, B: 159 - 271 (GenBank: 8777865)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | cloning artifact |
| Lys 2 | - | cloning artifact |
| Gln 3 | - | cloning artifact |
| Ser 4 | - | cloning artifact |
| Thr 5 | - | cloning artifact |
| Ile 6 | - | cloning artifact |
| Ala 7 | - | cloning artifact |
| Leu 8 | - | cloning artifact |
| Ala 9 | - | cloning artifact |
| Leu 10 | - | cloning artifact |
| Leu 11 | - | cloning artifact |
| Pro 12 | - | cloning artifact |
| Leu 13 | - | cloning artifact |
| Leu 14 | - | cloning artifact |
| Phe 15 | - | cloning artifact |
| Thr 16 | - | cloning artifact |
| Pro 17 | - | cloning artifact |
| Val 18 | - | cloning artifact |
| Thr 19 | - | cloning artifact |
| Lys 20 | - | cloning artifact |
| Ala 21 | - | cloning artifact |
| Arg 22 | - | cloning artifact |
| Arg 143 | - | linker |
| Gly 144 | - | linker |
| Gly 145 | - | linker |
| Gly 146 | - | linker |
| Gly 147 | - | linker |
| Ser 148 | - | linker |
| Gly 149 | - | linker |
| Gly 150 | - | linker |
| Gly 151 | - | linker |
| Gly 152 | - | linker |
| Ser 153 | - | linker |
| Gly 154 | - | linker |
| Gly 155 | - | linker |
| Gly 156 | - | linker |
| Gly 157 | - | linker |
| Ser 158 | - | linker |
| His 272 | - | cloning artifact |
| His 273 | - | cloning artifact |
| His 274 | - | cloning artifact |
| His 275 | - | cloning artifact |
| His 276 | - | cloning artifact |
| Gly 277 | - | cloning artifact |
| Leu 278 | - | cloning artifact |
| Val 279 | - | cloning artifact |
| Pro 280 | - | cloning artifact |
| Arg 281 | - | cloning artifact |
| Gly 282 | - | cloning artifact |
| Ser 283 | - | cloning artifact |
| Gly 284 | - | cloning artifact |
| Asp 285 | - | cloning artifact |
| Pro 286 | - | cloning artifact |
| Lys 287 | - | cloning artifact |
| Ala 288 | - | cloning artifact |
| Asp 289 | - | cloning artifact |
| Asn 290 | - | cloning artifact |
| Lys 291 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Leu 160 | Ile 2 | SEE REMARK 999 |
| Ser 231 | Pro 73 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 63008.6 | |
| All* | Total formula weight | 63008.6 |
