2GH5

Crystal Structure of human Glutathione Reductase complexed with a Fluoro-Analogue of the Menadione Derivative M5

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	glutathione reductase, mitochondrial	polymer	478	51636.2	2	UniProt (P00390) Pfam (PF00070) Pfam (PF02852)	Homo sapiens (human)	GR; GRase
2	C, D, L, M (A, B)	PHOSPHATE ION	non-polymer		95.0	4	Chemie (PO4)
3	E, N (A, B)	6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)HEXANOIC ACID	non-polymer		286.3	2	Chemie (ELI)
4	F, O (A, B)	FLAVIN-ADENINE DINUCLEOTIDE	non-polymer		785.5	2	Chemie (FAD)
5	G, H, I, J, K... (A, B)	GLYCEROL	non-polymer		92.1	12	Chemie (GOL)
6	W, X (A, B)	water	water		18.0	703	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	103272.5
Non-Polymers*	Number of molecules	20
	Total formula weight	3628.8
All*	Total formula weight	106901.2

*Water molecules are not included.