2GE9

Solution Structures of the SH2 domain of Bruton's Tyrosine Kinase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Tyrosine-protein kinase BTK	polymer	125	14350.0	1	UniProt (Q06187) Pfam (PF00017) In PDB	Homo sapiens (human)	Bruton's tyrosine kinase, Agammaglobulinaemia tyrosine kinase, ATK, B cell progenitor kinase, BPK

Sequence modifications

A: 1 - 118 (UniProt: Q06187)

PDB	External Database	Details
Met 0	-	initiating methionine
His 119	-	expression tag
His 120	-	expression tag
His 121	-	expression tag
His 122	-	expression tag
His 123	-	expression tag
His 124	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	14350.0
All*	Total formula weight	14350.0

*Water molecules are not included.