2GB4

Crystal structure of Thiopurine methyltransferase (18204406) from Mus musculus at 1.35 A resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Thiopurine S-methyltransferase	polymer	252	29086.3	2	UniProt (O55060) Pfam (PF05724)	Mus musculus (house mouse)	Thiopurine methyltransferase
2	C, D (A, B)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	2	Chemie (SAH)
3	E, F (A, B)	water	water		18.0	402	Chemie (HOH)

Sequence modifications

A, B: 1 - 240 (UniProt: O55060)

PDB	External Database	Details
Met -11	-	expression tag
Gly -10	-	expression tag
Ser -9	-	expression tag
Asp -8	-	expression tag
Lys -7	-	expression tag
Ile -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	58172.7
Non-Polymers*	Number of molecules	2
	Total formula weight	768.8
All*	Total formula weight	58941.5

*Water molecules are not included.