2G9N

Structure of the DEAD domain of Human eukaryotic initiation factor 4A, eIF4A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Eukaryotic initiation factor 4A-I	polymer	221	25087.3	2	UniProt (P60842) Pfam (PF00270) In PDB	Homo sapiens (human)	ATP-dependent RNA helicase eIF4A-1, eIF4A-I, eIF-4A-I
2		water	water		18.0	226	Chemie (HOH)

Sequence modifications

A, B: 20 - 238 (UniProt: P60842)

PDB	External Database	Details
Ser 18	-	cloning artifact
Met 19	-	cloning artifact
Mly 54	Lys 54	modified residue
Mly 68	Lys 68	modified residue
Mly 82	Lys 82	modified residue
Mly 99	Lys 99	modified residue
Mly 118	Lys 118	modified residue
Mly 146	Lys 146	modified residue
Mly 174	Lys 174	modified residue
Mly 177	Lys 177	modified residue
Mly 193	Lys 193	modified residue
Mly 202	Lys 202	modified residue
Mly 225	Lys 225	modified residue
Mly 226	Lys 226	modified residue
Mly 237	Lys 237	modified residue
Mly 238	Lys 238	modified residue

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	50174.6
All*	Total formula weight	50174.6

*Water molecules are not included.