2G9A
Structural basis for the specific recognition of methylated histone H3 lysine 4 by the WD-40 protein WDR5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | WD-repeat protein 5 | polymer | 311 | 34101.7 | 1 | UniProt (P61964) Pfam (PF00400) | Homo sapiens (human) | BMP2-induced 3-kb gene protein, WD-repeat protein BIG-3, WDR5 |
| 2 | B (B) | Histone H3 | polymer | 10 | 1204.4 | 1 |
Sequence modifications
A: 29 - 334 (UniProt: P61964)
| PDB | External Database | Details |
|---|---|---|
| Gly 24 | - | cloning artifact |
| Pro 25 | - | cloning artifact |
| Leu 26 | - | cloning artifact |
| Gly 27 | - | cloning artifact |
| Ser 28 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35306.1 | |
| All* | Total formula weight | 35306.1 |
