2G89
L. casei thymidylate synthase Y261A in complex with substrate, dUMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | thymidylate synthase | polymer | 316 | 36538.4 | 1 | UniProt (P00469) Pfam (PF00303) | Lactobacillus casei | TS, TSase |
| 2 | B (A) | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE | non-polymer | 308.2 | 1 | Chemie (UMP) | |||
| 3 | C (A) | water | water | 18.0 | 65 | Chemie (HOH) |
Sequence modifications
A: 1 - 316 (UniProt: P00469)
| PDB | External Database | Details |
|---|---|---|
| Ala 261 | Tyr 261 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36538.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 308.2 | |
| All* | Total formula weight | 36846.5 |
