2G6J
Structure of rat nNOS (L337N) heme domain (4-aminobiopterin bound) complexed with NO
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Nitric-oxide synthase, brain | polymer | 420 | 48613.2 | 2 | UniProt (P29476) Pfam (PF02898) In PDB | Rattus norvegicus (Norway rat) | NOS type I, Neuronal NOS, N-NOS, nNOS, Constitutive NOS, NC-NOS, BNOS |
| 2 | A, B | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 3 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | A, B | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 5 | A, B | (1S,2S)-1-(2,4-DIAMINOPTERIDIN-6-YL)PROPANE-1,2-DIOL | non-polymer | 236.2 | 2 | Chemie (7AP) | |||
| 6 | A, B | ARGININE | non-polymer | 175.2 | 2 | Chemie (ARG) | |||
| 7 | A, B | NITRIC OXIDE | non-polymer | 30.0 | 2 | Chemie (NO) | |||
| 8 | water | water | 18.0 | 342 | Chemie (HOH) |
Sequence modifications
A, B: 299 - 718 (UniProt: P29476)
| PDB | External Database | Details |
|---|---|---|
| Asn 337 | Leu 337 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 97226.4 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 2299.4 | |
| All* | Total formula weight | 99525.8 |
