2G5T
Crystal structure of human dipeptidyl peptidase IV (DPPIV) complexed with cyanopyrrolidine (C5-pro-pro) inhibitor 21ag
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Dipeptidyl peptidase 4 | polymer | 726 | 84252.3 | 2 | UniProt (P27487) Pfam (PF00930) Pfam (PF00326) In PDB | Homo sapiens (human) | Dipeptidyl peptidase IV, DPP IV, T-cell activation antigen CD26, TP103, Adenosine deaminase complexing protein 2, ADABP, Contains: Dipeptidyl peptidase 4 membrane form, Dipeptidyl peptidase IV membrane form, Dipeptidyl peptidase 4 soluble form, Dipeptidyl peptidase IV soluble form |
| 2 | A | 3-{[(2R,5S)-5-{[(2S)-2-(AMINOMETHYL)PYRROLIDIN-1-YL]CARBONYL}PYRROLIDIN-2-YL]METHOXY}-4-CHLOROBENZOIC ACID | non-polymer | 381.9 | 1 | Chemie (ACF) | |||
| 3 | water | water | 18.0 | 1421 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 168504.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 381.9 | |
| All* | Total formula weight | 168886.5 |
