2G59

Crystal Structure of the Catalytic Domain of Protein Tyrosine Phosphatase from Homo sapiens

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Receptor-type tyrosine-protein phosphatase O	polymer	297	34942.7	2	UniProt (Q16827) Pfam (PF00102) In PDB	Homo sapiens (human)	Glomerular epithelial protein 1, Protein tyrosine phosphatase U2, PTPase U2, PTP-U2
2	A	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
3		water	water		18.0	269	Chemie (HOH)

Sequence modifications

A, B: 3 - 289 (UniProt: Q16827)

PDB	External Database	Details
Met 1	-	expression tag
Ser 2	-	expression tag
Glu 290	-	expression tag
Gly 291	-	expression tag
His 292	-	expression tag
His 293	-	expression tag
His 294	-	expression tag
His 295	-	expression tag
His 296	-	expression tag
His 297	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	69885.3
Non-Polymers*	Number of molecules	2
	Total formula weight	189.9
All*	Total formula weight	70075.3

*Water molecules are not included.