2G1S
Ketopiperazine-Based Renin Inhibitors: Optimization of the C Ring
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Renin | polymer | 333 | 36566.2 | 2 | UniProt (P00797) Pfam (PF00026) | Homo sapiens (human) | Angiotensinogenase |
| 2 | C, E (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 3 | D, F (A, B) | (2S)-6-(2,4-DIAMINO-6-ETHYLPYRIMIDIN-5-YL)-2-(3,5-DIFLUOROPHENYL)-4-(3-METHOXYPROPYL)-2H-1,4-BENZOXAZIN-3(4H)-ONE | non-polymer | 469.5 | 2 | Chemie (4IG) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 370 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 73132.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1381.4 | |
| All* | Total formula weight | 74513.8 |
