2G1N
Ketopiperazine-based renin inhibitors: Optimization of the "C" ring
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Renin | polymer | 333 | 36566.2 | 2 | UniProt (P00797) Pfam (PF00026) In PDB | Homo sapiens (human) | Angiotensinogenase |
2 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
3 | A, B | N-{2-[6-(2,4-DIAMINO-6-ETHYLPYRIMIDIN-5-YL)-2,2-DIMETHYL-3-OXO-2,3-DIHYDRO-4H-1,4-BENZOTHIAZIN-4-YL]ETHYL}ACETAMIDE | non-polymer | 414.5 | 2 | Chemie (1IG) | |||
4 | water | water | 18.0 | 353 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 73132.5 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1271.5 | |
All* | Total formula weight | 74403.9 |