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2FZ9

Human Aldose Reductase complexed with inhibitor zopolrestat after six days soaking.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1Aaldose reductasepolymer31635898.31UniProt (P15121)
Pfam (PF00248)
In PDB
Homo sapiens (human)
2ANADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer743.41Chemie (NAP)
3A3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACIDnon-polymer419.41Chemie (ZST)
4waterwater18.0308Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight35898.3
Non-Polymers*Number of molecules2
Total formula weight1162.8
All*Total formula weight37061.1
*Water molecules are not included.

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PDB entries from 2024-07-24

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