2FYS

Crystal structure of Erk2 complex with KIM peptide derived from MKP3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (B, A)	Mitogen-activated protein kinase 1	polymer	364	42159.4	2	UniProt (P63086) Pfam (PF00069)	Rattus norvegicus (Norway rat)	Extracellular signal-regulated kinase 2, ERK-2, Mitogen-activated protein kinase 2, MAP kinase 2, MAPK 2, p42-MAPK, ERT1
2	C, D (D, C)	Dual specificity protein phosphatase 6	polymer	17	1939.4	2	UniProt (Q64346)		Mitogen-activated protein kinase phosphatase 3, MAP kinase phosphatase 3, MKP-3
3	E, F, G, H (B, A, D, C)	water	water		18.0	488	Chemie (HOH)

Sequence modifications

B, A: 2 - 358 (UniProt: P63086)

PDB	External Database	Details
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Met 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	88197.7
All*	Total formula weight	88197.7

*Water molecules are not included.