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2FXR

human beta tryptase II complexed with activated ketone inhibitor CRA-29382

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Tryptase beta-2polymer24527491.44UniProt (P20231)
Pfam (PF00089)
Homo sapiens (human)Tryptase-2, Tryptase II
2E, F, G, H
(A, B, C, D)
ALLYL {(1S)-1-[(5-{4-[(2,3-DIHYDRO-1H-INDEN-2-YLAMINO)CARBONYL]BENZYL}-1,2,4-OXADIAZOL-3-YL)CARBONYL]-3-PYRROLIDIN-3-YLPROPYL}CARBAMATEnon-polymer557.64Chemie (C3A)
3I, J, K, L
(A, B, C, D)
waterwater18.082Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight109965.7
Non-Polymers*Number of molecules4
Total formula weight2230.6
All*Total formula weight112196.3
*Water molecules are not included.

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PDB entries from 2025-06-11

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