2FVK

Crystal structure of dihydropyrimidinase from Saccharomyces kluyveri in complex with the substrate dihydrouracil

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	dihydropyrimidinase	polymer	559	62325.1	4	UniProt (Q9P903) Pfam (PF01979)	Lachancea kluyveri
2	E, F, H, I, K... (A, B, C, D)	ZINC ION	non-polymer		65.4	8	Chemie (ZN)
3	G, J, M, P (A, B, C, D)	DIHYDROPYRIMIDINE-2,4(1H,3H)-DIONE	non-polymer		114.1	4	Chemie (DUC)
4	Q, R, S, T (A, B, C, D)	water	water		18.0	1043	Chemie (HOH)

Sequence modifications

A, B, C, D: 2 - 542 (UniProt: Q9P903)

PDB	External Database	Details
Kcx 167	Lys 167	modified residue
Pro 543	-	expression tag
Gly 544	-	expression tag
Asp 545	-	expression tag
Asp 546	-	expression tag
Asp 547	-	expression tag
Asp 548	-	expression tag
Lys 549	-	expression tag
His 550	-	expression tag
His 551	-	expression tag
His 552	-	expression tag
His 553	-	expression tag
His 554	-	expression tag
His 555	-	expression tag
His 556	-	expression tag
His 557	-	expression tag
Ser 558	-	expression tag
Gly 559	-	expression tag
Asp 560	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	249300.4
Non-Polymers*	Number of molecules	12
	Total formula weight	979.7
All*	Total formula weight	250280.0

*Water molecules are not included.