2FUM
Catalytic domain of protein kinase PknB from Mycobacterium tuberculosis in complex with mitoxantrone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Probable serine/threonine-protein kinase pknB | polymer | 299 | 32458.5 | 4 | UniProt (P0A5S4) Pfam (PF00069) UniProt (by SIFTS) (P9WI81) | Mycobacterium tuberculosis H37Rv | PKNB SER/THR KINASE |
| 2 | E, F, G, H (A, B, C, D) | 1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE | non-polymer | 444.5 | 4 | Chemie (MIX) |
Sequence modifications
A, B, C, D: 1 - 279 (UniProt: P0A5S4)
| PDB | External Database | Details |
|---|---|---|
| Met -19 | - | cloning artifact |
| Gly -18 | - | cloning artifact |
| Ser -17 | - | cloning artifact |
| Ser -16 | - | cloning artifact |
| His -15 | - | cloning artifact |
| His -14 | - | cloning artifact |
| His -13 | - | cloning artifact |
| His -12 | - | cloning artifact |
| His -11 | - | cloning artifact |
| His -10 | - | cloning artifact |
| Ser -9 | - | cloning artifact |
| Ser -8 | - | cloning artifact |
| Gly -7 | - | cloning artifact |
| Leu -6 | - | cloning artifact |
| Val -5 | - | cloning artifact |
| Pro -4 | - | cloning artifact |
| Arg -3 | - | cloning artifact |
| Gly -2 | - | cloning artifact |
| Ser -1 | - | cloning artifact |
| His 0 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 129834.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1777.9 | |
| All* | Total formula weight | 131611.9 |
