2FST
mitogen activated protein kinase p38alpha (D176A+F327L) activating mutant
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | X | Mitogen-activated protein kinase 14 | polymer | 367 | 42165.1 | 1 | UniProt (Q16539) Pfam (PF00069) In PDB | Homo sapiens (human) | Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha, Cytokine suppressive anti-inflammatory drug binding protein, CSAID-binding protein, CSBP, MAX-interacting protein 2, MAP kinase MXI2, SAPK2A |
2 | X | octyl beta-D-glucopyranoside | non-polymer | 292.4 | 3 | Chemie (BOG) | |||
3 | water | water | 18.0 | 435 | Chemie (HOH) |
Sequence modifications
X: 2 - 360 (UniProt: Q16539)
PDB | External Database | Details |
---|---|---|
Met -6 | - | expression tag |
Ala -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
His -1 | - | expression tag |
His 0 | - | expression tag |
His 1 | - | expression tag |
Ala 176 | Asp 175 | engineered mutation |
Leu 327 | Phe 326 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 42165.1 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 877.1 | |
All* | Total formula weight | 43042.2 |