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2FSL

mitogen activated protein kinase p38alpha (D176A+F327S) activating mutant form-A

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1XMitogen-activated protein kinase 14polymer36742139.01UniProt (Q16539)
Pfam (PF00069)
In PDB
Homo sapiens (human)Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha, Cytokine suppressive anti-inflammatory drug binding protein, CSAID-binding protein, CSBP, MAX-interacting protein 2, MAP kinase MXI2, SAPK2A
2Xoctyl beta-D-glucopyranosidenon-polymer292.41Chemie (BOG)
3waterwater18.0207Chemie (HOH)
Sequence modifications
X: 2 - 360 (UniProt: Q16539)
PDBExternal DatabaseDetails
Met -6-expression tag
Ala -5-expression tag
His -4-expression tag
His -3-expression tag
His -2-expression tag
His -1-expression tag
His 0-expression tag
His 1-expression tag
Ala 176Asp 175engineered mutation
Ser 327Phe 326engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight42139.0
Non-Polymers*Number of molecules1
Total formula weight292.4
All*Total formula weight42431.4
*Water molecules are not included.

222036

PDB entries from 2024-07-03

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