2FRQ
Human Cathepsin S with Inhibitor CRA-26871
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | cathepsin S | polymer | 225 | 25006.0 | 2 | UniProt (P25774) Pfam (PF00112) In PDB | Homo sapiens (human) | |
| 2 | A, B | N-[4-(AMINOMETHYL)-1,1-DIOXIDOTETRAHYDRO-2H-THIOPYRAN-4-YL]-3-(1-METHYLCYCLOPENTYL)-N~2~-[(1E)-N-(PHENYLSULFONYL)ETHANIMIDOYL]-L-ALANINAMIDE | non-polymer | 512.7 | 2 | Chemie (C71) | |||
| 3 | water | water | 18.0 | 427 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 218 (UniProt: P25774)
| PDB | External Database | Details |
|---|---|---|
| Gly 219 | - | CLONING ARTIFACT |
| His 220 | - | CLONING ARTIFACT |
| His 221 | - | CLONING ARTIFACT |
| His 222 | - | CLONING ARTIFACT |
| His 223 | - | CLONING ARTIFACT |
| His 224 | - | CLONING ARTIFACT |
| His 225 | - | CLONING ARTIFACT |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 50012.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1025.4 | |
| All* | Total formula weight | 51037.4 |
