2FQ9
Cathepsin S with nitrile inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | cathepsin S | polymer | 225 | 25006.0 | 2 | GenBank (23110962) Pfam (PF00112) UniProt (by SIFTS) (P25774) In PDB | Homo sapiens (human) | |
2 | A, B | N-(1-CYANOCYCLOPROPYL)-3-({[(2S)-5-OXOPYRROLIDIN-2-YL]METHYL}SULFONYL)-N~2~-[(1S)-2,2,2-TRIFLUORO-1-(4-FLUOROPHENYL)ETHYL]-L-ALANINAMIDE | non-polymer | 490.5 | 2 | Chemie (CRJ) | |||
3 | water | water | 18.0 | 249 | Chemie (HOH) |
Sequence modifications
A, B: 0 - 218 (GenBank: 23110962)
PDB | External Database | Details |
---|---|---|
Gly 188 | - | EXPRESSION TAG |
His 189 | - | EXPRESSION TAG |
His 220 | - | EXPRESSION TAG |
His 221 | - | EXPRESSION TAG |
His 222 | - | EXPRESSION TAG |
His 223 | - | EXPRESSION TAG |
His 224 | - | EXPRESSION TAG |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 50012.1 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 980.9 | |
All* | Total formula weight | 50993.0 |