2FPB

Structure of Strictosidine Synthase, the Biosynthetic Entry to the Monoterpenoid Indole Alkaloid Family

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Strictosidine Synthase	polymer	322	36119.5	2	UniProt (P68175)	Rauvolfia serpentina (serpentwood)
2	C, D (A, B)	2-(1H-INDOL-3-YL)ETHANAMINE	non-polymer		160.2	2	Chemie (TSS)
3	E, F (A, B)	water	water		18.0	173	Chemie (HOH)

Sequence modifications

A, B: 23 - 344 (UniProt: P68175)

PDB	External Database	Details
Mse 65	Ile 65	engineered mutation
Mse 116	Leu 116	engineered mutation
Mse 180	Met 180	modified residue
Mse 190	Ile 190	engineered mutation
Mse 203	Leu 203	engineered mutation
Mse 276	Met 276	modified residue

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	72238.9
Non-Polymers*	Number of molecules	2
	Total formula weight	320.4
All*	Total formula weight	72559.3

*Water molecules are not included.