2FOI
Synthesis, Biological Activity, and X-Ray Crystal Structural Analysis of Diaryl Ether Inhibitors of Malarial Enoyl ACP Reductase.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | enoyl-acyl carrier reductase | polymer | 269 | 30364.4 | 2 | GenBank (23612231) Pfam (PF13561) UniProt (by SIFTS) (C6KSZ2) | Plasmodium falciparum | |
| 2 | C, D (C, D) | enoyl-acyl carrier reductase | polymer | 60 | 6829.7 | 2 | GenBank (23612231) Pfam (PF13561) UniProt (by SIFTS) (C6KSZ2) | Plasmodium falciparum | |
| 3 | E, G (A, B) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 2 | Chemie (NAD) | |||
| 4 | F, H (A, B) | 4-(2,4-DICHLOROPHENOXY)-2'-METHYLBIPHENYL-3-OL | non-polymer | 345.2 | 2 | Chemie (JPA) | |||
| 5 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 55 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 74388.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2017.3 | |
| All* | Total formula weight | 76405.4 |
