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2FNX

Design of Specific Peptide Inhibitors of Phospholipase A2 (PLA2): Crystal Structure of the Complex of PLA2 with a Highly Potent Peptide Val-Ile-Ala-Lys at 2.7A Resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Phospholipase A2 VRV-PL-VIIIapolymer12113629.81UniProt (P59071)
Pfam (PF00068)
Daboia russellii pulchellaPhosphatidylcholine 2- acylhydrolase, DPLA2
2B
(P)
Inhibitor peptidepolymer4430.61
3C
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
4D, E
(A, P)
waterwater18.057Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight14060.3
Non-Polymers*Number of molecules1
Total formula weight96.1
All*Total formula weight14156.4
*Water molecules are not included.

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PDB entries from 2025-12-17

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