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2FMZ

Carbonic anhydrase activators. Activation of isoforms I, II, IV, VA, VII and XIV with L- and D- phenylalanine, structure with D-Phenylalanine.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Carbonic anhydrase 2polymer26029289.11UniProt (P00918)
Pfam (PF00194)
Homo sapiens (human)Carbonic anhydrase II, Carbonate dehydratase II, CA-II, Carbonic anhydrase C
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C
(A)
MERCURY (II) IONnon-polymer200.61Chemie (HG)
4D
(A)
D-PHENYLALANINEnon-polymer165.21Chemie (DPN)
5E
(A)
waterwater18.0161Chemie (HOH)
Sequence modifications
A: 2 - 260 (UniProt: P00918)
PDBExternal DatabaseDetails
Met 1-initiating methionine
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight29289.1
Non-Polymers*Number of molecules3
Total formula weight431.2
All*Total formula weight29720.3
*Water molecules are not included.

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PDB entries from 2024-10-30

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