2FLB
Discovery of a Novel Hydroxy Pyrazole Based Factor IXa Inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | L | Coagulation factor VII | polymer | 152 | 17047.0 | 1 | UniProt (P08709) Pfam (PF00594) Pfam (PF00008) Pfam (PF14670) In PDB | Homo sapiens (human) | |
| 2 | H | Coagulation factor VII | polymer | 254 | 28103.3 | 1 | UniProt (P08709) Pfam (PF00089) In PDB | Homo sapiens (human) | |
| 3 | T | Tissue factor | polymer | 218 | 24739.4 | 1 | UniProt (P13726) Pfam (PF01108) Pfam (PF09294) In PDB | Homo sapiens (human) | TF, Coagulation factor III, Thromboplastin, CD142 antigen |
| 4 | H | 2-(4-HYDROXY-5-PHENYL-1H-PYRAZOL-3-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE | non-polymer | 318.3 | 1 | Chemie (6NH) | |||
| 5 | water | water | 18.0 | 321 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 69889.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 318.3 | |
| All* | Total formula weight | 70208.0 |
