2FIV
Crystal structure of feline immunodeficiency virus protease complexed with a substrate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | FELINE IMMUNODEFICIENCY VIRUS PROTEASE | polymer | 116 | 13248.3 | 2 | UniProt (P16088) Pfam (PF00077) | Feline immunodeficiency virus | FIV PR |
| 2 | C, D (I, J) | ACE-ALN-VAL-STA-GLU-ALN-NH2 | polymer | 7 | 822.0 | 2 | BIRD (PRD_000427) | FIV PROTEASE INHIBITOR LP-149 | |
| 3 | E, F (A, B) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | G, H, I, J (A, B, I, J) | water | water | 18.0 | 144 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 116 (UniProt: P16088)
| PDB | External Database | Details |
|---|---|---|
| Asn 30 | Asp 68 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 28140.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 192.1 | |
| All* | Total formula weight | 28332.7 |
