2FHR

Trypanosoma Rangeli Sialidase In Complex With 2,3- Difluorosialic Acid (Covalent Intermediate)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	sialidase	polymer	652	71205.2	1	GenBank (2894810) Pfam (PF13859) UniProt (by SIFTS) (O44049) In PDB	Trypanosoma rangeli
2	A	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
3	A	5-acetamido-3,5-dideoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid	non-polymer		327.3	1	Chemie (FSI)
4	A	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
5		water	water		18.0	388	Chemie (HOH)

Sequence modifications

A: 1 - 638 (GenBank: 2894810)

PDB	External Database	Details
Met -13	-	initiating methionine
Gly -12	-	cloning artifact
Gly -11	-	cloning artifact
Ser -10	-	cloning artifact
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
Gly -3	-	cloning artifact
Met -2	-	cloning artifact
Ala -1	-	cloning artifact
Ser 0	-	cloning artifact
Ile 50	Thr 72	SEE REMARK 999
Ala 186	Gly 208	SEE REMARK 999
Leu 372	Phe 394	SEE REMARK 999
Val 606	Ile 628	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	71205.2
Non-Polymers*	Number of molecules	4
	Total formula weight	611.5
All*	Total formula weight	71816.7

*Water molecules are not included.