2FGW
X-RAY STRUCTURES OF FRAGMENTS FROM BINDING AND NONBINDING VERSIONS OF A HUMANIZED ANTI-CD18 ANTIBODY: STRUCTURAL INDICATIONS OF THE KEY ROLE OF VH RESIDUES 59 TO 65
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | H52 FAB (LIGHT CHAIN) | polymer | 214 | 23475.0 | 1 | EMBL (X95750) | Homo sapiens (human) | |
| 2 | B (H) | H52 FAB (HEAVY CHAIN) | polymer | 232 | 24975.0 | 1 | Homo sapiens (human) |
Sequence modifications
L: 4 - 214 (EMBL: X95750)
| PDB | External Database | Details |
|---|---|---|
| Ser 14 | Phe 36 | CONFLICT |
| Asp 28 | Ser 50 | CONFLICT |
| Asn 30 | Ser 52 | CONFLICT |
| Asn 31 | Ser 53 | CONFLICT |
| Tyr 50 | Ala 72 | CONFLICT |
| Thr 51 | Ala 73 | CONFLICT |
| Thr 53 | Ser 75 | CONFLICT |
| His 55 | Gln 77 | CONFLICT |
| Tyr 71 | Phe 93 | CONFLICT |
| Gly 91 | Ser 113 | CONFLICT |
| Asn 92 | His 114 | CONFLICT |
| Thr 93 | Ser 115 | CONFLICT |
| Leu 94 | Thr 116 | CONFLICT |
| Pro 96 | Tyr 118 | CONFLICT |
| Lys 103 | Asn 125 | CONFLICT |
| Val 104 | Leu 126 | CONFLICT |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 48450.0 | |
| All* | Total formula weight | 48450.0 |
