2FFU
Crystal Structure of Human ppGalNAcT-2 complexed with UDP and EA2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Polypeptide N-acetylgalactosaminyltransferase 2 | polymer | 501 | 57129.8 | 1 | UniProt (Q10471) Pfam (PF00535) Pfam (PF00652) | Homo sapiens (human) | ppGalNAcT-2; Protein-UDP acetylgalactosaminyltransferase 2; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 2; Polypeptide GalNAc transferase 2; GalNAc-T2; pp-GaNTase 2 |
| 2 | B (P) | 13-Peptide EA2, PTTDSTTPAPTTK | polymer | 13 | 1318.4 | 1 | GenBank (995765) UniProt (by SIFTS) (Q63549) | ||
| 3 | C (A) | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
| 4 | D (A) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 1 | Chemie (UDP) | |||
| 5 | E, F (A, P) | water | water | 18.0 | 495 | Chemie (HOH) |
Sequence modifications
A: 75 - 571 (UniProt: Q10471)
| PDB | External Database | Details |
|---|---|---|
| Ser 71 | - | cloning artifact |
| Asp 72 | - | cloning artifact |
| Ala 73 | - | cloning artifact |
| Leu 74 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 58448.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 459.1 | |
| All* | Total formula weight | 58907.3 |
